
How does an analysis work?
How does an analysis work?
A microplastics analysis at NanoPlasticsLab follows a strictly controlled, ISO 9001–compliant workflow. Every step is documented and designed to ensure contamination-free, reproducible, and auditable results.
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On request, we provide a complete sampling kit: pre-rinsed and blank-tested glass bottles suitable for different matrices.
Both the bottles and the blanks can be verified individually if required.
Transport is organized so that no additional contamination risk is introduced.
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All steps use only MilLi-Q water, filtered multiple times through 200 nm membranes and continuously monitored.
Standard filtration is performed on specially coated membranes that:
show no Raman background, and
are optimized for the detection of nanoparticles.
Depending on the matrix, we apply cascaded filtration: multiple filters with decreasing pore sizes to pre-filter and fractionate particles.
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Staff wear cotton clothing, gloves, and protective gear to prevent plastic shedding.
All work is performed in laminar-flow clean air conditions.
Water, filters, and glassware are routinely checked.
Blanks are taken before and after each measurement to monitor background levels.
All staff receive regular training to maintain the highest standards.
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After preparation, particles remain directly on the coated membranes for measurement — avoiding transfer steps that might cause losses.
First, the sample is scanned with DeepMorph Imaging, an AI system that detects shape, size, and particle count.
Then, each identified particle is analyzed by Raman spectroscopy (RamanMetrix) and compared against our polymer library for accurate identification.
Standard data analysis: Principal Component Analysis (PCA) and Pearson correlation – transparent, auditable, and robust.
Optional (R&D only): advanced machine learning models (CNNs, Random Forests, etc.) for pattern recognition and exploratory insights.
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Suspicious material (e.g., from packaging or production sites) can be submitted.
Using a specialized machine-learning database, we can assign likely sources of microplastic particles.
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Every measurement includes negative and positive controls.
Methods are regularly checked with spiked reference samples (irregular PET, PE, PS, PVC nanoplastics).
On request, we validate methods for the customer’s matrix to ensure auditable and forensically robust data.
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Customers receive a detailed PDF report including:
Total number of particles (absolute & normalized)
Size distribution & morphology (form, length, diameter)
Polymer identification (PET, PE, PS, PVC, etc.)
Optional: statistical analyses (PCA, Pearson correlation)
Optional: Compliance report ready for integration into quality systems (e.g., cGMP).
Raw data can also be provided for research or publication purposes.